Neurontin is a derivative of GABA used to relieve pain

Gabapentin is a drug that exhibits anticonvulsant and analgesic activity. It is prescribed for patients with epileptic seizures, as well as for people who suffer from neuropathic pain. The principle of its action is not fully understood, but the drug performed well during preclinical studies.

Action of Gabapentin

Gabapentin is structurally similar to gamma-aminobutyric acid (GABA), which is an important inhibitory neurotransmitter in the human body. It is found in the central nervous system and takes part in some brain processes. However, Gabapentin is different from other drugs that bind to GABA receptors. It reduces the flow of calcium ions, which plays an important role in the formation of neuropathic pain. Additionally, Gabapentin enhances the production of GABA and also opens ion channels for potassium ions. Potassium provides a general strengthening effect on the nervous and muscular systems.

Active Ingredient: Gabapentin

Diseases:

• Pain
• Diabetic
• Neuropathies
• Neuralgia
• Neuropathy
• Neuropathic
• Pain
• Seizure
• Partial
• Seizures
• Epilepsy

Indications for use

Gabapentin is prescribed for the following conditions:

• treatment of partial seizures with secondary generalization in people over 12 years of age (both monotherapy and as part of combination treatment);
• neuropathic pain in patients over 18 years of age.

In some cases, Gabapentin is used to treat an anxiety disorder. This is the so-called off-label therapy, that is, the use of a drug whose instructions do not mention the corresponding effects. Sale Gabapentin is used in complex therapy of patients with bipolar disorder (not to regulate manic and depressive phases, but to reduce the overall level of anxiety). The drug can also be used for the treatment of pendulum nystagmus (involuntary high-frequency eye movements), for hormonal changes during menopause, in the complex therapy of multiple sclerosis and to alleviate withdrawal symptoms. Gabapentin has proven effective against restless legs syndrome, as well as some types of tremors.

Gabapentin in complex therapy of treatment-resistant focal epilepsy

Focal epilepsy is a type of epilepsy in which clear and localized foci with so-called paroxysmal activity form in the human brain. When examined on an electroencephalogram, wave-like jumps in the electrical activity of the cerebral cortex are recorded. Focal epilepsy is the most common type of epilepsy. Attacks in this disease have varying degrees of attack intensity. Gabapentin as part of complex therapy shows good results, reducing attacks by 50% or more. But research in this area is insufficient and requires more detailed consideration to understand the effectiveness of Gabapentin in the long term.

Adverse reactions

Gabapentin is a potent drug and can affect the central nervous system, causing symptoms such as:

• dizziness;
• involuntary movement of the eyeballs (nystagmus);
• tremor;
• motor disorder;
• speech impairment;
• memory loss;
• tics;
• depressive state;
• unpleasant sensations in the body (tingling, burning, crawling sensations).

In addition, Gabapentin may affect:

• cardiovascular system, relaxing the smooth wall of blood vessels;
• the digestive system, causing dyspepsia, appetite disorders, dry mouth and digestive tract disorders;
• musculoskeletal system, causing pain in muscles and joints;
• sensory organs, causing tinnitus and visual disturbances;
• respiratory system, causing runny nose, sore throat and cough (in combination therapy with other drugs for epilepsy);
• the genitourinary system, causing erectile dysfunction and, in rare cases, urinary incontinence.

In exceptional cases, when taking Gabapentin without a prescription, a decrease in the number of white blood cells and allergic reactions may occur.

Precautionary measures

In patients who have suicidal thoughts and are taking Gabapentin, treatment should be carried out under strict medical supervision. The effect of this drug on the nervous system can aggravate depression and lead to suicide attempts.

Abuse of Gabapentin can lead to addiction. When trying to abruptly discontinue the drug, withdrawal syndrome is observed (withdrawal syndrome, as in drug addiction and alcoholism).

When using Gabapentin, it is not recommended to drive a car or work with complex instruments and equipment, since taking the drug leads to a decrease in concentration.

Dosage of Gabapentin

Gabapentin cost is taken orally (by mouth), without chewing and with plenty of water. Reception does not depend on food intake. If you need to reduce the dosage or completely cancel it, you need to contact your doctor, who will prescribe a gradual dose reduction over the course of a week.

For neuropathic pain in patients over 18 years of age, the initial dose is 900 mg of the drug per day. This dose should be divided into three doses. If necessary, Gabapentin orders are taken up to 3600 mg per day. For some patients, the initial daily dose is administered gradually.

This happens as follows:

1. First day: 300 mg 1 time per day.
2. Second day: 300 mg 2 times a day.
3. Third day: 300 mg 3 times a day.

When treating epilepsy with partial seizures, patients over 12 years of age are prescribed a dose in the range of 900-2400 mg per day. The dose is also administered gradually, and the maximum interval between doses should not be more than 12 hours, in order to avoid the occurrence of convulsive attacks. The decision to increase the dosage above 2400 mg per day is made by the doctor, but it should be no more than 3600 mg per day.

In case of renal failure, the doctor prescribes a dosage reduction regimen based on the level of creatinine in the urine. If the patient is on hemodialysis, it is recommended to take the drug 200-300 mg every 4 hours of hemodialysis.

Overdose

When using Gabapentin cheap above the maximum daily dosage, a person may experience the following sensations:

• severe dizziness;
• speech impairment;
• loss of strength and drowsiness;
• stomach upset;
• double vision.

Treatment begins with gastric lavage and taking activated charcoal, and then medications are prescribed to relieve acute symptoms. If the patient has renal failure, then hemodialysis is also necessary.

Interaction with other drugs

Gabapentin may be prescribed with medications such as:

• other medicines for the treatment of epilepsy;
• drugs that interfere with the excretion of Gabapentin in the urine;
• birth control pills (containing ethinyl estradiol or norethidrone);

When taking morphine and Gabapentin at the same time, medical supervision is necessary to monitor for side effects. In this case, the dose of both drugs is reduced gradually.

Buy Gabapentin

Gabapentin can be purchased in our online pharmacy (ordered to your home) without a doctor’s prescription. In addition, the cost of the drug is cheaper than in a regular pharmacy, because we offer a high-quality analogue – generic Gabapentin delivered by mail. It is developed on the basis of a similar active ingredient and does not differ from the original drug in action.

Benefits of generic Gabapentin

Generic Gabapentin has a lower price due to the fact that all the necessary research (development, preclinical and clinical trials, trial launch of the drug and correction of production errors) was carried out earlier. All such costs are included in the cost of the drug. The over-the-counter generic Gabapentin was released after the patent of the original drug expired, and is based on an already studied active ingredient. Therefore, it is a good and affordable drug with proven effectiveness, and at the same time has a low cost.

Neurontin/Gabapentin other names: Abaglin Algia Alidial Alpentin Apo gab Bapex Blugat Bosrontin Brilian Dineurin Edion Epiven Epleptin Equipax Gabadoz Gabagamma Gabahasan Gabahexal Gabalept Gabalich Gabamerck Gabanet Gabaneural Gabantin Gabapen Gabapentina Gabapentine Gabapentinum Gabapin Gabaran Gabaront Gabastad Gabatal Gabatem Gabateva Gabatin Gabatine Gabator Gabatur Gabax Gabental Gabentin Gabex Gabexal Gabexine Gabictal Gabin Gabiton Gaboton Gabrion Gabtin Gabture Galepsi Ganin Gantin Gapentek Gapentin Gapridol Garbapia Gatilox Gordius Kaptin Katena Logistic Medivapom Mirgy Mycovit gb Nepatic Neugabin Neurexal Neuril Neurogabin Neuropen Neuros Neurostil Neurotin Nopatic Normatol Nupentin Nurabax Pendine Progresse Rangabax Ritmenal Semerial Symleptic Tebantin Ultraneutral Yalipent Zincobal

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